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Rnafh study until now has been the first prospective, randomized controlled, open-label study initiated by investigator to explore the effect of rosuvastatin 10 mg d versus blank control for 52 weeks on ihcl evaluated by 1 h-mrs in nafld patients with ms but without overt diabetes.

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Chronic alcohol liver disease is known to increase rosuvastatin exposure; rosuvastatin calcium should be used with caution in these patients see contraindications , warnings and precautions , and clinical pharmacology .

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Rosuvastatin calcium should be used with caution in patients who consume substantial quantities of alcohol and or have a history of chronic liver disease see clinical pharmacology .

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rosuvastatin therapy was closely followed by pravastatin in reducing ldl and total cholesterol; however, atorvastatin was found to be the least effective in reducing both ldl and total cholesterol as compared with other statins among patients with mets.

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